Use of Hyaluronic Acid Gel in Intraosseous Defects

HA gel was applied to the periodontal pockets where the intraosseous defect was located using a sterile injector with a plastic needle. The gel was applied until it overflowed from the gingival sulcus. Patients were instructed not to eat, drink or brush their teeth for at least one hour. Subgingival application of HA was repeated 4 weeks after the first session.

The control group received placebo HA gel probe without rinsing. Placebo application was repeated 4 weeks after the first session.