Comparison of Emergence Delirium: Remimazolam vs Sevoflurane Anesthesia

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

February 29, 2024

Primary Completion Date

February 28, 2025

Study Completion Date

March 31, 2025

Conditions
Emergence Delirium
Interventions
DRUG

Remimazolam

Anesthesia induction:intravenous Fentanyl 2-3 μg/kg, remimazolam 0.3-0.5 mg/kg and Rocuronium 0.6mg/kg; Maintenance of anesthesia:Remimazolam will infuse initially at a rate of 2 mg/kg/h (1-3 mg/kg/h), and remifentanil will administer at an initial infusion rate of 0.25 μg/kg/min (0.1-0.5 μg/kg/min).

DRUG

Sevoflurane

Anesthesia induction: Anesthesia will induce with 8% sevoflurane in 100% oxygen at flow rate of 6 L/min, and then intravenous fentanyl (2-3 μg/kg) and rocuronium (0.6 mg/kg); Maintenance of anaesthesia: Anesthesia depth will maintain at 1-1.5 minimum alveolar concentration (MAC), and remifentanil was infuse at an initial rate of 0.25 μg/kg/min (0.1-0.5 μg/kg/min).

Trial Locations (1)

Unknown

The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou

All Listed Sponsors
lead

Second Affiliated Hospital of Wenzhou Medical University

OTHER

NCT06214117 - Comparison of Emergence Delirium: Remimazolam vs Sevoflurane Anesthesia | Biotech Hunter | Biotech Hunter