Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

October 1, 2024

Study Completion Date

November 1, 2024

Conditions
Post Spinal Anesthesia Hypotension
Interventions
DRUG

Norepinephrine

after spinal anesthesia, norepinephrine will be injected intravenous as bolus at 0.05 μg/kg, followed by norepinephrine infusion at a rate of 0.05 μg/kg.min to prevent post spinal hypotension

DRUG

Midodrine

10 mg tablets of midodrine 1 hour before spinal anesthesia to prevent post spinal anesthesia hypotension

All Listed Sponsors
lead

Sohag University

OTHER

NCT06213935 - Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial | Biotech Hunter | Biotech Hunter