NCT06209047View on ClinicalTrials.gov

Bronchoscopic Levofloxacin, Gentamicin, or Sham for Acute Exacerbation of Bronchiectasis

PHASE4RecruitingINTERVENTIONAL
Enrollment

315

Participants

Timeline

Start Date

October 15, 2023

Primary Completion Date

May 15, 2026

Study Completion Date

February 1, 2027

Conditions
Bronchiectasis With Acute Exacerbation
Interventions
DRUG

Local instillation of gentamicin and Budesonide

Bronchoscopic local instillation of gentamicin and Budesonide

DRUG

Local instillation of Levofloxacin and Budesonide

Bronchoscopic local instillation of Levofloxacin and Budesonide

PROCEDURE

Bronchoscopic mechanical secretion suction and lavage

Bronchoscopic mechanical secretion suction and lavage

PROCEDURE

Sham Bronchoscopy

Bronchoscopy for airway visualization only, no lavage or drug instillation (sham procedure).

Trial Locations (1)

71515

RECRUITING

Assiut university hospitals, Asyut

All Listed Sponsors
lead

Assiut University

OTHER