The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 21, 2023

Primary Completion Date

December 30, 2024

Study Completion Date

June 30, 2025

Conditions
Anesthesia Recovery PeriodPostoperative Complications
Interventions
DRUG

Dexmedetomidine and propofol

Group 1: After anesthesia induction, dexmedetomidine was infused at 1 μg/kg intravenously within 15 min, then infused at 0.3 μg/kg/h until 30 min before the end of the operation. Meantime, propofol was infused at 4-12mg/kg/h intravenously to maintain the depth of anesthesia.

DRUG

Dexmedetomidine and desflurane

Group 2: After anesthesia induction, dexmedetomidine was infused at 1 μg/kg intravenously within 15 min, then infused at 0.3 μg/kg/h until 30 min before the end of the operation. At the same time, 2.5%-8.5% desflurane was inhaled to maintain the depth of anesthesia.

Trial Locations (2)

400000

RECRUITING

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

RECRUITING

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

All Listed Sponsors
lead

The Second Affiliated Hospital of Chongqing Medical University

OTHER