Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

October 19, 2023

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Gastric CancerGastroesophageal Junction Adenocarcinoma
Interventions
DRUG

Infigratinib

Infigratinib is a selective ATP-competitive inhibitor of fibroblast growth factor receptor (FGFR) 1-3 that inhibits FGFR downstream signaling and proliferation in human cancer cell lines with FGFR genetic alterations, significantly inhibiting the growth of several types of cancers driven by FGFR amplification, fusion and mutation.

Trial Locations (30)

100142

Beijing Cancer Center, Beijing

110002

The First Hospital of China Medical University, Shenyang

130012

Jilin Cancer Hospital, Changchun

150081

Harbin Medical University Cancer Hospital, Harbin

200032

Zhongshan Hospital Fudan University, Shanghai

210008

Nanjing Drum Tower Hospital, Nanjing

230031

Anhui Provincial Cancer Hospital, Hefei

230601

The Second Hospital of Anhui Medical University, Hefei

250013

Central Hospital Affiliated to Shandong First Medical University, Jinan

250117

Shandong Provincial Cancer Hosptial, Jinan

266000

The Affiliated Hospital of Qingdao University, Qingdao

300060

Tianjin Medical University Cancer Institute&Hospital, Tianjin

310013

The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

410002

Hunan Provincial People's Hospital, Changsha

430030

Tongji Hospital, Tongji Medical College of HUST, Wuhan

430079

Hubei Cancer Hospital, Wuhan

450052

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

510180

Guangzhou First People's Hospital, Guangzhou

510655

The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou

523059

Dongguan City People's Hospital, Dongguan

541199

The Second Affiliated Hospital of Guilin Medical University, Guilin

545006

Liuzhou People's Hospital, Liuzhou

610041

West China Hospital of Sichuan University, Chengdu

610042

Sichuan Cancer Hospital, Chengdu

650118

Yunnan Cancer Hospital, Kunming

730030

The Second Hospital Lanzhou University, Lanzhou

Unknown

The First Affiliated Hospital of Xiamen University, Xiamen

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an

071030

Affiliated Hospital of Hebei University, Baoding

030013

Shanxi Provincial Cancer Hospital, Taiyuan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

LianBio LLC

INDUSTRY