Intensive Neurowave Emotional Stimulation (INES)

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

December 14, 2023

Primary Completion Date

December 14, 2024

Study Completion Date

September 15, 2025

Conditions
Disorders of Consciousness
Interventions
DEVICE

Intensive Neurowave Emotional Stimulation (INES)

Patients will undergo Neurowave-assisted multisensory stimulation five days a week for four weeks, featuring emotionally significant audio-visual content tied to personal history. Control group participants will experience primary auditory stimulation through familiar sounds, following a traditional rehabilitation approach mimicking the experimental group's frequency and intensity but without Neurowave use. This allows for a meaningful comparison of the two groups' experiences.

OTHER

Intensive Sensorial Emotional Stimulation (ISES)

The Intensive Sensorial Emotional Stimulation (ISES) in the control group involves primary auditory stimulation with emotionally rich everyday sounds, including familiar voices, favorite songs, and sounds related to daily life and past activities. It mimics the experimental group's frequency and intensity, lasting 45 minutes per session, five days a week, for four weeks. Unlike the experimental group using Neurowave, the control group follows a traditional rehabilitation approach with paper materials, live photos, face-to-face interaction, and classic music tapes, facilitating a meaningful comparison between the two groups' experiences.

Trial Locations (1)

98124

RECRUITING

IRCCS Centro Neurolesi Bonino Pulejo, Messina

All Listed Sponsors
lead

IRCCS Centro Neurolesi Bonino Pulejo

OTHER

NCT06204172 - Intensive Neurowave Emotional Stimulation (INES) | Biotech Hunter | Biotech Hunter