Comparing Endoscopic Strictureplasty vs. Balloon Dilation in Crohn's Disease Strictures

NARecruitingINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

December 16, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

January 1, 2026

Conditions
Crohn Disease
Interventions
PROCEDURE

endoscopic stricturoplasty

Experimental Group: In the experimental group, 51 patients underwent endoscopic stricturoplasty. A transparent cap was mounted on the front end of the endoscope, and a needle knife was inserted through the working channel of the endoscope. Under direct visualization, a radial incision was made at the site of the stricture, with an effort to preserve normal mucosal tissue as much as possible. The stricture was gradually incised until the endoscope could smoothly pass through.

PROCEDURE

endoscopic balloon dilation

Control Group: In the control group, 51 patients underwent endoscopic balloon dilation. The endoscope was advanced to the site of the stricture, and a dilation guidewire was inserted. After placing the balloon, it was progressively inflated with pressure, each inflation lasting 1-2 minutes, and this process was repeated 2-3 times until the endoscope and sheath could pass through the narrowed segment and enter the distal colon.

Trial Locations (1)

310000

RECRUITING

浙江大学医学院第二附属医院, Hangzhou

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER