Evaluation of Phacogoniotomy in Medically-controlled POAG

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 28, 2023

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2029

Conditions
Glaucoma, Open-AngleCataract ComplicatedGoniotomy
Interventions
PROCEDURE

PEI+GT

After a standard phacoemulsification with intraocular lens implantation (PEI) is performed. The viscoelastic substance will be injected into the anterior chamber again to maintain corneal rigidity. The surgical microscope will be adjusted to tilt 35-40° towards the patient's nasal side, and the patient's head position will be adjusted to tilt 35-40° accordingly. A viscoelastic substance will be applied to the corneal surface to facilitate direct visualization of the angle structures under a gonioscope. The Tanito Microhook will be inserted through the main incision into the anterior chamber, and under gonioscopic guidance, the nasal (or inferonasal) trabecular meshwork and the inner wall of Schlemm's canal will be incised, approximately 120° in extent (60° in each direction).

PROCEDURE

PEI+MED

Participants assigned to control group will undergo routine PEI surgery. Postoperatively, the decision to administer anti-glaucoma medication is based on intraocular pressure (IOP) measurements, and the target IOP is set at 16 mmHg. The selection of medications is informed by the Asia Pacific Glaucoma Guidelines (Kugler Publications, 2016), while the target IOP reference is the European Glaucoma Guidelines.

Trial Locations (1)

510060

RECRUITING

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou

All Listed Sponsors
collaborator

West China Hospital

OTHER

collaborator

Chongqing Medical University

OTHER

collaborator

The Second Hospital of Anhui Medical University

OTHER

collaborator

Handan City Eye Hospital

UNKNOWN

collaborator

Shijiazhuang People's Hospital

OTHER

collaborator

Chengdu First People's Hospital

OTHER

collaborator

Guangdong Hospital of Traditional Chinese Medicine, Zhuhai

UNKNOWN

collaborator

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong

OTHER

collaborator

Huizhou Municipal Central Hospital

OTHER

lead

Sun Yat-sen University

OTHER