100
Participants
Start Date
September 28, 2023
Primary Completion Date
September 30, 2026
Study Completion Date
December 31, 2029
PEI+GT
After a standard phacoemulsification with intraocular lens implantation (PEI) is performed. The viscoelastic substance will be injected into the anterior chamber again to maintain corneal rigidity. The surgical microscope will be adjusted to tilt 35-40° towards the patient's nasal side, and the patient's head position will be adjusted to tilt 35-40° accordingly. A viscoelastic substance will be applied to the corneal surface to facilitate direct visualization of the angle structures under a gonioscope. The Tanito Microhook will be inserted through the main incision into the anterior chamber, and under gonioscopic guidance, the nasal (or inferonasal) trabecular meshwork and the inner wall of Schlemm's canal will be incised, approximately 120° in extent (60° in each direction).
PEI+MED
Participants assigned to control group will undergo routine PEI surgery. Postoperatively, the decision to administer anti-glaucoma medication is based on intraocular pressure (IOP) measurements, and the target IOP is set at 16 mmHg. The selection of medications is informed by the Asia Pacific Glaucoma Guidelines (Kugler Publications, 2016), while the target IOP reference is the European Glaucoma Guidelines.
RECRUITING
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou
West China Hospital
OTHER
Chongqing Medical University
OTHER
The Second Hospital of Anhui Medical University
OTHER
Handan City Eye Hospital
UNKNOWN
Shijiazhuang People's Hospital
OTHER
Chengdu First People's Hospital
OTHER
Guangdong Hospital of Traditional Chinese Medicine, Zhuhai
UNKNOWN
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
OTHER
Huizhou Municipal Central Hospital
OTHER
Sun Yat-sen University
OTHER