Continuous Local-anesthetic Wound Infusion for Neck Dissection

NANot yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

August 31, 2025

Study Completion Date

December 31, 2025

Conditions
Head and Neck Cancer
Interventions
DRUG

0.5% Lidocaine Hydrochloride

Prior to the end of neck dissection and any additional procedures, the bilateral catheter will be placed adjacent to the cervical plexus underneath the internal jugular vein, left in place for 24 hours and removed in a similar way to the Redon drainage by the surgeon. The CWI block will start immediately at a speed of 4ml/h containing 0.5% lidocaine hydrochloride + 1:400000 adrenaline.

DRUG

0.9% Normal Saline

Prior to the end of neck dissection and any additional procedures, the bilateral catheter will be placed adjacent to the cervical plexus underneath the internal jugular vein, left in place for 72 hours and removed in a similar way to the Redon drainage by the surgeon. The CWI placebo will start immediately at a speed of 4ml/h containing 0.9% normal saline + 1:400000 adrenaline.

All Listed Sponsors
lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

NCT06201039 - Continuous Local-anesthetic Wound Infusion for Neck Dissection | Biotech Hunter | Biotech Hunter