NCT06197178View on ClinicalTrials.gov

A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)

PHASE1RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

December 28, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

March 31, 2028

Conditions
Advanced Gastrointestinal Tumors
Interventions
BIOLOGICAL

LCAR-G08 cells

Prior to infusion of the LCAR-G08, subjects will receive a conditioning premedication regimen consisting of cyclophosphamide and fludarabine.

Trial Locations (2)

100142

RECRUITING

Beijing Cancer Hospital & Institute, Beijing

102200

RECRUITING

Beijing GoBroad Hospital, Beijing

Sponsors
All Listed Sponsors
collaborator

Nanjing Legend Biotech Co.

INDUSTRY

lead

Peking University

OTHER