Effects of Medical Treatment of ICAS With Hemodynamic Disorders Based on MR-FFR

RecruitingOBSERVATIONAL
Enrollment

400

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions
Stroke, IschemicIntracranial Atherosclerosis
Interventions
DRUG

Standard Medical Treatment on the basis of anti-platelet therapy

"1. Anti-platelet therapy: aspirin 75mg+clopidogrel 100mg will be applied for patients with severe ICAS stenosis (70%-90%) suffering stroke or TIA within 30 days. After 90 days, single anti-platelet therapy will be continued.~2. Intensive statin therapy: Statins with high doses~3. Blood pressure: below 140/90mmHg~4. LDL: less than 1.81mmol/L(70mg/dl)~5. Fasting blood glucose controlled to 5.9mmol/L, and glycosylated hemoglobin A1c reduced to less than 7%~6. Cigarette and alcohol quitting~7. Oral anticoagulants for atrial fibrillation"

Trial Locations (1)

Unknown

RECRUITING

Xuanwu Hospital, Capital Medical University, Beijing

All Listed Sponsors
collaborator

National Key Research and Development Project, China

UNKNOWN

lead

Xuanwu Hospital, Beijing

OTHER