1,424
Participants
Start Date
July 19, 2024
Primary Completion Date
November 19, 2026
Study Completion Date
November 19, 2026
Rivaroxaban 10 MG
"Administration of rivaroxaban 10 mg once daily to prevent venous thromboembolic events in patients with trauma to a lower limb.~Consecutive patients with lower limb trauma and a TRiP(cast) score ≥ 7 are assessed for possible participation in the study. At the inclusion visit, if the patient meets the study's selection criteria, the investigator provides oral and written information (information letter written in a language the patient can understand) and answers any questions the patient may have. Depending on randomisation, the patient will receive either LMWH or rivaroxaban. The dose is rivaroxaban 10 mg orally once a day (no dosage adjustment).~Treatment is started in the emergency department and continued at home for the duration of the immobilisation (i.e. until mobilisation with weight-bearing). The duration of treatment will be determined by the physician."
Low Heparin Molecular Weight
"Administration of standard prophylactic anticoagulant treatment with LMWH for the duration of immobilisation (i.e. until full mobilisation with weight-bearing). Consecutive patients with lower limb trauma and a TRiP(cast) score ≥ 7 are assessed for possible participation in the study. At the inclusion visit, if the patient meets the study's selection criteria, the investigator provides oral and written information (information letter written in a language the patient can understand) and answers any questions the patient may have. Depending on randomisation, the patient will receive either LMWH or rivaroxaban. The dose of LMWH is free, given according to local practices and national recommendations.~Treatment is started in the emergency department and continued at home for the duration of the immobilisation (i.e. until mobilisation with weight-bearing). The duration of treatment will be determined by the physician."
NOT_YET_RECRUITING
Marseille University Hospital, Emergency department, Marseille
WITHDRAWN
Caen University hospital, Emergency department, Caen
NOT_YET_RECRUITING
La Rochelle Hospital, Adult emergency departement, La Rochelle
NOT_YET_RECRUITING
Eure-Seine Hospital, Emergency Departement, Évreux
RECRUITING
Toulouse University Hospital, Emergency Department, Toulouse
RECRUITING
Montpellier University Hospital, emergency department, Montpellier
RECRUITING
Rennes University Hospital, Emergency department, Rennes
NOT_YET_RECRUITING
Tours University Hospital, Emergency department, Chambray-lès-Tours
RECRUITING
Grenoble University Hospital, Emergency Department, Grenoble
RECRUITING
Nantes University Hospital, Emergency department, Nantes
NOT_YET_RECRUITING
Agen-Nerac Hospital, Emergency Department, Agen
RECRUITING
Angers University Hospital, Emergency department, Angers
RECRUITING
Cholet Hospital, Emergency department, Cholet
RECRUITING
Clermont-Ferrand University Hospital, Emergency department, Clermont-Ferrand
RECRUITING
Strasbourg University Hospital, Emergency Department, Strasbourg
RECRUITING
Edouard Herriot University Hospital, Emergency Department, Lyon
RECRUITING
South Lyon University Hospital, Emergency department, Pierre-Bénite
RECRUITING
Le Mans Hospital, Emergency department, Le Mans
NOT_YET_RECRUITING
Lariboisière hospital, emergency department, Paris
RECRUITING
Saint-Antoine Hospital, Emergency department, Paris
NOT_YET_RECRUITING
La Pitié-Salpétrière Hospital, Emergency Department, Paris
RECRUITING
Cochin Hospital, Emergency department, Paris
RECRUITING
St-Joseph Hospital, Emergency Department, Paris
RECRUITING
HEGP, Emergency Department, Paris
NOT_YET_RECRUITING
Bichat Hospital, Adult Emergency department, Paris
NOT_YET_RECRUITING
Rouen University Hospital, Emergency Department, Rouen
RECRUITING
Niort Hospital, Emergency Department, Niort
RECRUITING
Poitiers University Hospital, Emergency department, Poitiers
RECRUITING
Limoges University hospital, Emergency department, Limoges
NOT_YET_RECRUITING
Arpajon Hospital, Emergency Department, Arpajon
RECRUITING
Argenteuil hospital, Emergency department, Argenteuil
RECRUITING
Simone Veil Hospital, Emergency Department, Eaubonne
WITHDRAWN
Nice University Hospital, Emergency department, Nice
University Hospital, Angers
OTHER_GOV