800
Participants
Start Date
January 1, 2020
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2028
dabrafenib plus trametinib with or without PD-1 antibody
advanced thyroid cancer patients who harbor BRAF V600E mutation
entrectinib or larotrectinib with or without anti-PD-1 antibdoy
advanced thyroid cancer patients who harbor NTRK mutation
pralsetinib or selpercatinib with or without anti-PD-1 antibdoy
advanced thyroid cancer patients who harbor RET fusion or medullary thyroid carcinoma patients who habor RET mutation.
anlotinib or anlotinib plus anti-PD-1 antibody
For patients with medullary carcinoma, if there is no RET gene mutation or RET gene mutation is unknown
lenvatinib plus anti-PD-1 antibody
Advanced thyroid cancer patients who don't harbor the above gene mutation or could not afford the cost of precision treatment even with the above gene mutation
Other Targets: precise treatment based on the target
Advanced thyroid cancer patients who had other treatment targets not included above
RECRUITING
Peking union medical college hospital, Beijing
RECRUITING
Fudan University Shanghai Cancer Center, Shanghai
RECRUITING
Fujian Cancer Hospital, Fuzhou
RECRUITING
Henan Cancer Hospital, Zhengzhou
RECRUITING
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan
RECRUITING
Zhejiang Cancer Hospital, Hangzhou
RECRUITING
Caixia Liu, Hohhot
RECRUITING
Shanxi Cancer Hospital, Shanxi
Peking Union Medical College Hospital
OTHER
Shanxi Province Cancer Hospital
OTHER
Henan Cancer Hospital
OTHER_GOV
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Zhejiang Cancer Hospital
OTHER
The Affiliated Hospital of Inner Mongolia Medical University
OTHER
Ruijin Hospital
OTHER
Fujian Cancer Hospital
OTHER_GOV
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
Shanghai 6th People's Hospital
OTHER
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
OTHER
Shanghai 10th People's Hospital
OTHER
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
OTHER
Changhai Hospital
OTHER
Tianjin Medical University Cancer Institute and Hospital
OTHER
Jiangsu Cancer Institute & Hospital
OTHER
The First Affiliated Hospital of Anhui University of Chinese Medicine
OTHER
Hunan Provincial People's Hospital
OTHER
Dalian Friendship Hospital Affiliated to Dalian Medical University
UNKNOWN
The Third Affiliated Hospital of Soochow University
OTHER
Sun Yat-sen University
OTHER
Liaoning Cancer Hospital & Institute
OTHER
Sir Run Run Shaw Hospital
OTHER
Fudan University
OTHER