NCT06194851View on ClinicalTrials.gov

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

PHASE2RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

October 28, 2024

Primary Completion Date

April 30, 2028

Study Completion Date

April 30, 2028

Conditions
Post-Traumatic Stress Disorder (PTSD)
Interventions
DRUG

Oxytocin nasal spray

Veteran participants will self-administer 40 IU of intranasal oxytocin 30 minutes before the start of each bCBCT session.

DRUG

Saline nasal spray

Veteran participants will self-administer 40 IU of the placebo (intranasal saline spray) 30 minutes before the start of each bCBCT session.

BEHAVIORAL

Brief Cognitive-Behavioral Conjoint Therapy

Eight sessions of standardized bCBCT, a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning.

Trial Locations (1)

92161-0002

RECRUITING

VA San Diego Healthcare System, San Diego, CA, San Diego

All Listed Sponsors
lead

VA Office of Research and Development

FED