Incidence of Postoperative Residual Curarization

CompletedOBSERVATIONAL
Enrollment

90

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Neuromuscular Blockade, Residual
Interventions
PROCEDURE

measurement of train of four ratio (TOFR) to assess residual neuromuscolar block

Upon arrival of the spontaneously breathing patient in the Post-Anesthesia Care Unit, a researcher will evaluate the TOFR to detect any residual neuromuscular block using the acceleromyographic method at the level of thumb adductor.2 TOFR measurements will be performed 30 seconds apart. If the difference between the two measurements will be ≤ 0.1, the average value will be considered for the purposes of the analysis. In case of a difference \> 0.1, a third measurement will be taken and the average of the two closest results will be considered. If a residual block is detected sugammadex will be administered (2 mg/kg in the case of at least 2 contraction responses to TOF stimulation or 4 mg/kg in the case of no contraction response) to restore normal neuromuscular function , assessed by subsequent TOFR measurement.

Trial Locations (1)

00100

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

NCT06193213 - Incidence of Postoperative Residual Curarization | Biotech Hunter | Biotech Hunter