Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Women Undergoing In-vitro Fertilization

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

February 14, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
IVF
Interventions
PROCEDURE

Controlled Ovarian Stimulation Protocol

"Ovarian Stimulation Process:~* Stimulate ovaries with FSH \& hMG (150-375 IU) starting day 2-3 of menstruation.~* Monitor response with ultrasound \& hormones (E2, LH, P4).~* GnRH-ant arm: Prevent LH surge with Cetrorelix (0.25mg) starting day 5.~* PPOS arm: Suppress LH with Dydrogesterone (10mg x 3/day) from day 1.~* Trigger ovulation when ≥2 follicles \>17mm (Triptorelin, hCG, or rhCG).~* Oocyte retrieval 36-38 hours later (\>10mm follicles aspirated).~Embryo Culture \& Monitoring:~* Fertilize with ICSI.~* Culture \& evaluate embryos (43-45 hours, day 3/5).~* Freeze all embryos."

Trial Locations (1)

700000

RECRUITING

Univesity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City

All Listed Sponsors
lead

Hanoi Medical University

OTHER