Impact of Gravity on Cardiac Hemodynamics

NARecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

November 22, 2023

Primary Completion Date

June 22, 2025

Study Completion Date

October 15, 2025

Conditions
Diabetes type1Healthy
Interventions
OTHER

Cardiovascular and Baroreflex stimulation by Tilting

Tilt of the patient at 4 angles (22°, 42°, 58° and 80°), the order is randomized for 3 angles (22°, 42°, 58°) while 80° will always be last.

OTHER

Cardiovascular and Baroreflex stimulation by Lower Body Negative Pressure

The patient will undergo 4 level of LBNP (10Torr, 20Torr, 35Torr, 50Torr), the order is randomized for 3 intensities (10Torr, 20Torr, 35Torr) while 50Torr will always be last.

Trial Locations (1)

14000

RECRUITING

Inserm 1075 Comete, Unicaen, Caen

All Listed Sponsors
collaborator

INSERM UMR-S 1075 COMETE, Caen, France

UNKNOWN

collaborator

CNRS UMR 5220 INSERM U1294 CREATIS ,Université Lyon 1, INSA Lyon, France

UNKNOWN

collaborator

Jozef Stefan Institute

OTHER

lead

University Hospital, Caen

OTHER