Thoracic Consolidation Radiotherapy for ES-SCLC Treated With Chemo-immunotherapy

PHASE1RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

December 31, 2025

Conditions
Small Cell Lung Cancer Extensive Stage
Interventions
RADIATION

thoracic radiotherapy

"Thoracic radiotherapy should begin within 42 days after the end of the last chemotherapy at an initial dose of 30 Gy in 10 fractions (3 patients).~Dose escalation will start after acceptable safety was observed, first at: 35 Gy/10 Fx(3 patients), then to the next dose group: 40 Gy/10 Fx(22 patients). Radiotherapy was administered between two immunotherapy doses (3 weeks interval) to avoid thoracic radiotherapy on the same day with immunotherapy."

Trial Locations (1)

200030

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER