Stratifying Psychoses for Personalized REpetitive TMS in Persistent NEgative Symptoms Alleviation

NANot yet recruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

November 1, 2028

Study Completion Date

November 1, 2028

Conditions
SchizophreniaPersistent Negative SymptomsProgressive Periodic CatatoniaAviationApathy
Interventions
PROCEDURE

Personalized rTMS

"5 personalized targets accessible to TMS (at less than 3.5 cm distance from the scalp or the coil's hot spot) are placed in the hyper-perfused premotor regions.~The patient is installed on the robotic device. The technician puts a neuro-navigation tracker on the subject's forehead and proceeds to the co-registration. The motor threshold is defined, and stimulator output's intensity is adjusted accordingly (120%) The robotic system ensures that the actual stimulation is performed according to the personalized protocol. This adequacy will be evaluated secondarily based on the recordings of the coil positions during each"

All Listed Sponsors
lead

University Hospital, Strasbourg, France

OTHER

NCT06184165 - Stratifying Psychoses for Personalized REpetitive TMS in Persistent NEgative Symptoms Alleviation | Biotech Hunter | Biotech Hunter