Effect of ERCC and/or PEEP-ZEEP Maneuver on Oxygenation, Ventilation, and Airway Secretions Removal in MV Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

May 31, 2024

Study Completion Date

August 31, 2024

Conditions
Mechanically Ventilated Patients
Interventions
OTHER

Expiratory Rib Cage Compression

Expiratory rib cage compression (ERCC) In this study, ERCC is a technique consisting of bilateral manual compression of the lower rib cage (anterolateral region of the chest at the level of the six last ribs) gradually during the expiratory phase of the ventilatory cycle and release from the compression at the end of the expiration.

OTHER

PEEP-ZEEP Maneuver

PEEP-ZEEP maneuver In this study, PEEP-ZEEP maneuver refers to PEEP which stands for positive end-expiratory pressure, and ZEEP which stands for zero end-expiratory pressure. In this maneuver PEEP will be incremented to 15 cmH2O throughout five consecutive respiratory cycles, then immediately after the inspiratory phase of the fifth cycle has been ended ZEEP should be done by abruptly reducing PEEP value to 0 cmH2O. The PEEP-ZEEP maneuver should be performed in two sets, consisting of a total of 10 consecutive breathing cycles. Subsequently, the patient is ventilated according to his/her baseline ventilator parameters.

OTHER

ERCC + PEEP-ZEEP maneuver

\- The ERCC technique will be applied as mentioned above, then followed by PEEP-ZEEP maneuvers according to the standard steps mentioned before.

All Listed Sponsors
lead

Damanhour University

OTHER

NCT06182553 - Effect of ERCC and/or PEEP-ZEEP Maneuver on Oxygenation, Ventilation, and Airway Secretions Removal in MV Patients | Biotech Hunter | Biotech Hunter