NCT06178627View on ClinicalTrials.gov

Amphotericin B for Non-HIV Cryptococcal Meningitis Patients

PHASE4Enrolling by invitationINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

August 13, 2023

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2026

Conditions
Cryptococcal MeningitisAntifungal Agents
Interventions
DRUG

Amphotericin B 0.5 mg/kg/day i.v. combined with flucytosine four times per day orally for the first 4 weeks.

Different amphotericin B dosage

DRUG

Amphotericin B 0.7 mg/kg/day i.v. combined with flucytosine four times per day orally for the first 4 weeks.

Different amphotericin B dosage

Trial Locations (2)

200040

Huashan Hospital, Shanghai

530000

The Fourth People's Hospital of Nanning, Nanning

All Listed Sponsors
lead

Huashan Hospital

OTHER