New Perspective on Exploring the Post-apneic BP Surge in Patients With OSA

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

April 1, 2024

Study Completion Date

June 1, 2024

Conditions
Obstructive Sleep Apnea
Interventions
DRUG

Phentolamine Injection

Under patient safety, Phentolamine will be pumped into the OSA patients equipped with PSG and ECG monitoring in a safe dose to prevent sympathetic overactivity. Under patient safety, Nitroglycerin will be pumped into the OSA patients equipped with PSG and ECG monitoring in a safe dose to prevent endothelial dysfunction.

Trial Locations (1)

223300

RECRUITING

Jing Xu, Huai'an

All Listed Sponsors
lead

Xu J

OTHER