Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy

NACompletedINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

April 30, 2024

Study Completion Date

April 30, 2024

Conditions
CiprofolHysteroscopy
Interventions
DRUG

Ciprofol group

All patients received 5 μ g of sufentanil 1 minute before intravenous infusion of ciprofol, followed by intravenous injection of ciprofol (0.4mg/kg). When the MOAA/S score is ≤ 1, vaginal disinfection begins. During the induction of sedation, the MOAA/S score is evaluated every 30 seconds. If the MOAA/S score remains above 1, a supplementary dose of 1/2 of the initial dose is injected within 10 seconds. During the maintenance phase, supplementary doses are given when there are signs of physical activity, eye opening, or speech. If more than 5 additional doses are required within 15 minutes, painless hysteroscopy is considered a failure, and propofol is immediately used to enhance sedation.

DRUG

Propofol group

All patients received 5 μ g of sufentanil 1 minute before intravenous infusion of propofol, followed by intravenous injection of propofol (2 mg/kg) for 30 seconds. When the MOAA/S score is ≤ 1, vaginal disinfection begins. During the induction of sedation, the MOAA/S score is evaluated every 30 seconds. If the MOAA/S score remains above 1, a supplementary dose of 1/2 of the initial dose is injected within 10 seconds. During the maintenance phase, supplementary doses are given when there are signs of physical activity, eye opening, or speech. If more than 5 additional doses are required within 15 minutes, painless hysteroscopy is considered a failure, and propofol is immediately used to enhance sedation.

Trial Locations (1)

510120

Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen Universit, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT06172140 - Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy | Biotech Hunter | Biotech Hunter