Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

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National Taiwan University Cancer Center (NTUCC) ( Site 3907), Taipei City

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National Taiwan University Hospital - Hsinchu branch ( Site 3901), Hsinchu

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National Cheng Kung University Hospital-Clinical Trial Center ( Site 3903), Tainan City

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Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 3904), Kaohsiung City

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Westmead Hospital ( Site 3000), Westmead

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Port Macquarie - Mid North Coast Cancer Institute-Medical Oncology ( Site 3002), Port Macquarie

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Northern Hospital ( Site 3003), Epping

COMPLETED

Grampians Health-Medical Oncology ( Site 3001), Ballarat Central

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Odense Universitetshospital ( Site 1200), Odense C

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Regionshospitalet Gødstrup-Kræftklinikken ( Site 1204), Herning

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Aalborg Universitetshospital, Syd-Department of Oncology ( Site 1201), Aalborg

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National Taiwan University Hospital-Oncology ( Site 3906), Taipei

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Chulalongkorn University-Medicine ( Site 4003), Bangkok

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National Cancer Center ( Site 3801), Goyang-si

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Mackay Memorial Hospital ( Site 3909), Taipei

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Faculty of Medicine Siriraj Hospital ( Site 4000), Bangkok

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Hospital Jerez de la Frontera-UGC Oncología ( Site 2333), Jerez de la Frontera

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Higiea Oncologia ( Site 0721), Mexico City

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Hôpital Saint Joseph-ONCOLOGY ( Site 1308), Marseille

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Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 1402), Berlin

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CHUAC-Hospital Teresa Herrera-MEDICAL ONCOLOGY ( Site 2335), A Coruña

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Clinica Vallesur - AUNA ( Site 0854), Arequipa

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IPOR Instituto Peruano de Oncología & Radioterapia-Centro de Investigación ( Site 0851), Lima

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Detecta Clínica ( Site 0853), Surquillo

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INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 0850), Lima

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The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 3800), Suwon

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Ajou University Hospital-Hematology-Oncology ( Site 3806), Suwon

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Pamukkale University Medical Faculty, Fahri Goksin Oncology Centre-Oncolgyy-Hematology ( Site 2510), Denizli

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Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1800), Milan

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LungenClinic Grosshansdorf-Onkologie ( Site 1401), Großhansdorf

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Wonju Severance Christian Hospital ( Site 3808), Wŏnju

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Hospital La Princesa ( Site 2338), Madrid

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HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2331), Pozuelo de Alarcón

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Chungbuk National University Hospital-Internal medicine ( Site 3804), Cheongju-si

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H.R.U Malaga - Hospital General ( Site 2332), Málaga

COMPLETED

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0106), Marietta

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Medizinische Hochschule Hannover-Department of Pneumology ( Site 1411), Hanover

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Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0133), Jacksonville

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"P.O. S. Maria della Misericordia Azienda Sanitaria Univers-Oncology Department ( Site 1803)", Udine

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Medipol Mega Universite Hastanesi-oncology ( Site 2508), Stanbul

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Institut Régional du Cancer Montpellier-Medical Oncology ( Site 1309), Montpellier

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TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2502), Istanbul

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Universitätsklinikum Marburg-Comprehensive Cancer Center ( Site 1412), Marburg

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Ege Universitesi Hastanesi-Chest Diseases Department ( Site 2503), Bornova

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Erciyes University ( Site 2511), Talas

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Hattiesburg Clinic Hematology/Oncology ( Site 0104), Hattiesburg

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The University of Louisville, James Graham Brown Cancer Center ( Site 0121), Louisville

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Taichung Veterans General Hospital-Chest ( Site 3905), Taichung

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HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 2337), Seville

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Keimyung University Dongsan Hospital CRC room 1 ( Site 3807), Daegu

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University Hospitals Cleveland Medical Center ( Site 0119), Cleveland

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CIO - Centro de Inmuno-Oncología de Occidente ( Site 0715), Guadalajara

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Fundación Instituto Valenciano de Oncología-Oncologico ( Site 2336), Valencia

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"IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) Dino Amadori-Oncologia Medica ( Site 1807)", Meldola

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Bethanien Krankenhaus Moers ( Site 1400), Moers

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Universitätsklinikum Münster - Albert Schweitzer Campus-Medizinische Klinik A ( Site 1410), Münster

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Maharaj Nakorn Chiang Mai Hospital-Chiang Mai Clinical Trial Unit (CM-CTU) ( Site 4001), Chiang Mai

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Centre d'Oncologie de Gentilly ( Site 1301), Nancy

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Universitätsmedizin Johannes Gutenberg Universität Mainz- Klinik für Pneumologie ( Site 1404), Mainz

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Ondokuz Mayıs Universitesi ( Site 2509), Samsun

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Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0115), Minneapolis

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Mayo Clinic - Rochester ( Site 0148), Rochester

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Axis Heilsa S. de R.L. de C.V. ( Site 0719), Monterrey

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Centre Hospitalier de la Côte Basque ( Site 1300), Bayonne

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Oaxaca Site Management Organization S.C. ( Site 0718), Oaxaca City

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L HOPITAL NORD OUEST ( Site 1310), Gleizé

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Instituto Tumori Giovanni Paolo II-SSD Oncologia Medica per la Patologia Toracica ( Site 1804), Bari

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Clinica Integral Internacional de Oncología ( Site 0714), Puebla City

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Chi Mei Hospital - Liouying Branch ( Site 3908), Tainan City

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Oncology Consultants P.A. ( Site 0129), Houston

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Centro de Atención e Investigación Cardiovascular del Potosí ( Site 0713), San Luis Potosí City

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Clinique de l'Europe-Service de pneumologie ( Site 1304), Amiens

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Klinikum der Ludwig-Maximilians-Universitaet Muenchen-Medizinische Klinik V ( Site 1409), München

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Cancer Centers of Colorado St. Mary's Regional Hospital ( Site 0132), Grand Junction

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Klinikum Bogenhausen-Klinik für Pneumologie und Onkologische Pneumologie ( Site 1406), München

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Chang Gung Memorial Hospital at Kaohsiung ( Site 3902), Kaohsiung City

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Mayo Clinic in Arizona - Phoenix ( Site 0147), Phoenix

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Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 1305), Poitiers

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Centre Hospitalier Universitaire de Limoges - Hôpital Dupuyt-Unité d'oncologie thoracique et cutané ( Site 1303), Limoges

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AOU Renato Dulbecco ( Site 1801), Catanzaro

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Renown Regional Medical Center-Renown Health Medical Oncology ( Site 0134), Reno

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Klinikum Nürnberg Nord-5. Med. Klinik ( Site 1407), Nuremberg

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Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0130), Burbank

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Good Samaritan Regional Medical Center-Samaritan Pastega Regional Cancer Center ( Site 0117), Corvallis

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K Hospital - National Cancer Hospital ( Site 4174), Hanoi

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National Lung Hospital-Oncology Department ( Site 4175), Hanoi

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Tam Anh General Hospital ( Site 4179), Hanoi

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Beijing Cancer hospital-intrathoratic deparmtment II ( Site 3101), Beijing

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Beijing Peking Union Medical College Hospital-pneumology department ( Site 3100), Beijing

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FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0600), Bogotá

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Jilin Province Tumor Hospital-oncology department ( Site 3126), Changchun

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Harbin Medical University Cancer Hospital-oncology of department ( Site 3132), Harbin

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Shanghai Changhai Hospital ( Site 3125), Shanghai

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Affiliated Hospital of Jiangnan University(Wuxi Fourth People's Hospital ) ( Site 3113), Wuxi

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The Affiliated Hospital of Xuzhou Medical College ( Site 3112), Xuzhou

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Second Affiliated hospital of Anhui Medical University ( Site 3133), Hefei

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IMAT S.A.S ( Site 0602), Montería

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Jinan Central Hospital-oncology department ( Site 3122), Jinan

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Shandong Cancer Hospital ( Site 3119), Jinan

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The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 3115), Hangzhou

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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine ( Site 3111), Hangzhou

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Taizhou Hospital of Zhejiang Province-Respiratory ( Site 3114), Taizhou

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The First Affiliated Hospital of Nanchang University-Respiratory Medicine Department ( Site 3127), Nanchang

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The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 3121), Nanchang

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Jiangxi Provincial Cancer Hospital ( Site 3143), Nanchang

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Fujian Provincial Cancer Hospital ( Site 3131), Fuzhou

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The First Affiliated hospital of Xiamen University-Breast Surgery ( Site 3107), Xiamen

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The Second Xiangya Hospital of Central South University ( Site 3138), Changsha

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Tongji Hospital Tongji Medical,Science & Technology ( Site 3117), Wuhan

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Wuhan Union Hospital ( Site 3130), Wuhan

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Hubei Cancer Hospital ( Site 3106), Wuhan

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Xiangyang Central Hospital-oncology department ( Site 3136), Xiangyang

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Henan Cancer Hospital ( Site 3116), Zhengzhou

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The First Affiliated Hospital of Guangzhou Medical University ( Site 3134), Guangzhou

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Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 3108), Guangzhou

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Affiliated Hospital of Guangdong Medical University ( Site 3123), Zhanjiang

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West China Hospital, Sichuan University ( Site 3124), Chengdu

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Sichuan Cancer hospital. ( Site 3105), Chengdu

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The Second People's Hospital of Neijiang ( Site 3140), Neijiang

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Yunnan Province Cancer Hospital ( Site 3139), Kunming

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Oncologos del Occidente ( Site 0603), Pereira

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Thong Nhat Hospital ( Site 4170), Ho Chi Minh City

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Cho Ray Hospital ( Site 4171), Ho Chi Minh City

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Ho Chi Minh City Oncology Hospital - Tan Phu Ward ( Site 4173), Ho Chi Minh City

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Bradford Hill Norte ( Site 0516), Antofagasta

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Clinica Universidad Catolica del Maule-Oncology ( Site 0501), Talca

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Orlandi Oncologia-Oncology ( Site 0504), Santiago

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FALP-UIDO ( Site 0509), Santiago

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Bradfordhill-Clinical Area ( Site 0507), Santiago

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Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0402), Barretos

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Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 0406), São José do Rio Preto

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New England Cancer Specialists ( Site 0143), Westbrook

COMPLETED

University of Massachusetts Chan Medical School-Division of Hematology/Oncology ( Site 0144), Worcester

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Instituto Alexander Fleming ( Site 0306), Ciudad Autónoma de Buenos Aires

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Hospital Británico de Buenos Aires-Oncology ( Site 0304), Buenos Aires

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Centro Privado de RMI Río Cuarto S.A. II ( Site 0310), Río Cuarto

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Instituto de Oncología de Rosario ( Site 0301), Rosario

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Hospital Aleman-Oncology ( Site 0300), Buenos Aires

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Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0409), Porto Alegre

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Clinica Viver ( Site 0400), Santa Maria

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Instituto Nacional de Câncer - INCA ( Site 0405), Rio de Janeiro

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Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 0401), São Paulo

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William Osler Health System ( Site 0203), Brampton

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Trillium Health Partners - Credit Valley Hospital ( Site 0202), Mississauga

ACTIVE_NOT_RECRUITING

McGill University Health Centre ( Site 0200), Montreal

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The Second Hospital of Hebei Medical University ( Site 3135), Shijiazhuang

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Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni oddeleni ( Site 1103), Ostrava

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Multiscan-Onkologicke a radiologicke centrum Multiscan Pardubice ( Site 1105), Pardubice

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Vseobecna fakultni nemocnice v Praze-Onkologicka klinika ( Site 1106), Prague

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Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 1102), Olomouc

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SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1403), Gera

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1806), Roma

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Fujita Health University Hospital ( Site 3411), Toyoake

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Hirosaki University Hospital ( Site 3429), Hirosaki

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National Cancer Center Hospital East ( Site 3403), Kashiwa

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National Hospital Organization Shikoku Cancer Center ( Site 3415), Matsuyama

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National Hospital Organization Kyushu Cancer Center ( Site 3417), Fukuoka

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Kurume University Hospital ( Site 3418), Kurume

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Gunma Prefectural Cancer Center ( Site 3402), Ōta

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National Hospital Organization Himeji Medical Center ( Site 3426), Himeji

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Iwate Medical University Hospital ( Site 3428), Shiwa-gun

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St. Marianna University Hospital ( Site 3421), Kawasaki

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Yokohama Municipal Citizen's Hospital ( Site 3425), Yokohama

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Kanagawa Cancer Center ( Site 3408), Yokohama

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Matsusaka Municipal Hospital ( Site 3422), Matsusaka

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Tohoku University Hospital ( Site 3424), Sendai

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Sendai Kousei Hospital ( Site 3400), Sendai

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Kansai Medical University Hospital ( Site 3412), Hirakata

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Osaka Medical and Pharmaceutical University Hospital ( Site 3413), Takatsuki

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National Hospital Organization Ureshino Medical Center ( Site 3427), Ureshino

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Niigata Cancer Center Hospital ( Site 3409), Niigata

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Shizuoka Cancer Center ( Site 3410), Suntogun

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Dokkyo Medical University Hospital ( Site 3401), Shimotsugagun

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Tokyo Metropolitan Komagome Hospital ( Site 3405), Bunkyo

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Cancer Institute Hospital of JFCR ( Site 3404), Koto

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Toho University Omori Medical Center ( Site 3420), Ōta-ku

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Tokyo Medical University Hospital ( Site 3407), Shinjuku

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National Center for Global Health and Medicine ( Site 3406), Shinjuku

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National Hospital Organization Yamaguchi Ube Medical Center ( Site 3423), Ube

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National Hospital Organization Kyushu Medical Center ( Site 3416), Fukuoka

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Saiseikai Kumamoto Hospital ( Site 3419), Kumamoto

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Osaka International Cancer Institute ( Site 3414), Osaka

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Amphia Ziekenhuis, locatie Breda Molengracht-long oncologie ( Site 1901), Breda

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ETZ Elisabeth-Department of Pulmonary Diseases ( Site 1902), Tilburg

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Isala, locatie Zwolle-Poli Longziekten ( Site 1903), Zwolle

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Hospital Cayetano Heredia-Oncology ( Site 0855), Lima

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Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz

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Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 2013), Grudziądz

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Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 2016), Torun

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Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 2015), Krakow

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Instytut Gruźlicy i Chorób Płuc w Warszawie-3rd Dep of Lung Diseases and Oncology ( Site 2011), Warsaw

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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warsaw

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Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001), Przemyśl

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SPZOZ Uniwersytecki Szpital Kliniczny Im. Wojskowej Akademii Medycznej UM W Łodzi Centralny Szpital ( Site 2012), Lodz

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Instituto Português de Oncologia de Lisboa Francisco Gentil ( Site 2104), Lisbon

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Unidade Local de Saude de Santa Maria - Hospital Pulido Valente ( Site 2101), Lisbon

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Hospital Dr. Nélio Mendonça ( Site 2105), Funchal

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Unidade Local de Saude Gaia/Espinho - Hospital Eduardo Santos Silva ( Site 2103), Vila Nova de Gaia

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Hospital CUF - Tejo ( Site 2100), Lisbon

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Asan Medical Center-Lung Cancer Center ( Site 3805), Seoul

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Samsung Medical Center-Division of Hematology/Oncology ( Site 3802), Seoul

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Hospital Universitari Vall d'Hebron-Oncology ( Site 2330), Barcelona

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Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 2507), Adana

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Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi-oncology ( Site 2506), Ankara

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Hacettepe Universite Hastaneleri-oncology hospital ( Site 2501), Ankara

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Memorial Ankara Hastanesi-Medical Oncology ( Site 2505), Ankara

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Ankara Bilkent Şehir Hastanesi ( Site 2500), Ankara

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Royal Free Hospital ( Site 2601), London

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Queen Alexandra Hospital-Oncology Department ( Site 2603), Portsmouth

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Kent and Canterbury Hospital-Oncology Research ( Site 2606), Canterbury

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Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials ( Site 2605), London

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James Cook University Hospital ( Site 2604), Central Middlesbrough