Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 3, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

August 31, 2026

Conditions
Chronic Fatigue Syndrome
Interventions
OTHER

APA program

An APA program of 12 weeks, 2 sessions of 1h/week for mixed endurance, strengthening and stretching work. The program can be realized at home or in structure.

OTHER

Active transcutaneous VNS

After each APA session, a 1h-tVNS session is delivered on the conchae aurea of the left ear, in resting condition. Parameters of tVNS : frequency 20Hz, impulsion 200ms, amplitude 1mA below the unpleasant sensation level.

OTHER

Sham transcutaneous VNS

After each APA session, a 1h-tVNS session is delivered on the left earlobe, in resting condition. Parameters of tVNS : frequency 20Hz, impulsion 200ms, amplitude 1mA below the unpleasant sensation level.

Trial Locations (1)

42055

RECRUITING

Centre Hospitalier de Saint-Etienne, Saint-Etienne

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER