Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Arterial HypertensionResistant HypertensionMicrovascular FunctionNitrate Supplementation
Interventions
DIETARY_SUPPLEMENT

Beetroot extract

Beetroot extract powder supplementation with 400mg of nitrate per dose in the amount of 10g per day orally will be used in the group.

DIETARY_SUPPLEMENT

Placebo

The placebo will be administered as a colored and flavored isocaloric supplement composed of maltodextrin.

Trial Locations (1)

21040-360

RECRUITING

National Institute of Cardiology, Rio de Janeiro

All Listed Sponsors
lead

National Institute of Cardiology, Laranjeiras, Brazil

OTHER_GOV