Comparing CO2 Laser and Electrosurgical Treatments for Perianal Condyloma

NANot yet recruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Perianal Wart
Interventions
PROCEDURE

CO2 LASER Vaporisation

The CO2 LASER vaporization procedure is described as follows. Patient positioning will be done, and patient will be anesthetized. Local infiltration with 2% lidocaine, nerve block or general anesthesia will be given. The surgical field will be disinfected and draped. The perianal and anal area will be investigated for lesion. CO2 LASER from 20 cm distance in a continuous wave mode and 20 W power will be applied. After warts melts, necrotic tissue will be removed. After the operation was completed, residual debris will be wiped away with a piece of moist gauze. Bacitracin cream applied over the treated areas. Upon discharge acetaminophen 1-gram q8 and Ibuprofen 600 q8 for pain.

PROCEDURE

Electrosurgical Fulguration

The procedure is described as follows. Patient will be administered regional or general anesthesia, placed in prone jack-knife position. Prepping and draping will be done. The perianal and anal area will be investigated for lesion. The lesions will be excised, and the bases will be fulgurated. Electrosurgery device will be used in monopolar setting (30 Cut mode, 30 Coag mode). After procedure local analgesics total MERCAINE/EPI 0.25% 20 ml on both sides of the lesion. Bacitracin cream applied over the treated areas. Upon discharge 1000 mg of Tylenol every 8 hours along with 600 mg of ibuprofen every 8 hours.

All Listed Sponsors
lead

University of Illinois at Chicago

OTHER

NCT06166290 - Comparing CO2 Laser and Electrosurgical Treatments for Perianal Condyloma | Biotech Hunter | Biotech Hunter