A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps

PHASE2CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

December 18, 2023

Primary Completion Date

July 7, 2025

Study Completion Date

July 22, 2025

Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG

Verekitug (UPB-101)

Verekitug (UPB-101) 0.5 mL of formulated solution (100 mg verekitug \[UPB-101\])

DRUG

Placebo

Verekitug (UPB-101) matching placebo

Trial Locations (41)

10117

Charite Universitaetsmedizin Berlin, Berlin

11021

Northwell Health/Division of Allergy and Immunology, Great Neck

11407

Hospital Universitario de Jerez de la Frontera, Cadiz

21162

Chesapeake Clinical Research, Inc., White Marsh

28015

Hospital Universitario Fundacion Jimenez Diaz (UAM-FJD) Consultas Externas Isaac Peral, Madrid

28034

Hospital Universitario Ramón y Cajal, Madrid

29303

Spartanburg /Greer ENT & Allergy, Spartanburg

33013

Novaceut Clinical Research, Miami

33024

Alfa Medical Research, Hollywood

33173

Well Pharma Medical Research Corp., Miami

33176

IMIC Inc., Miami

40220

Advanced ENT and Allergy, Louisville

41009

Hospital Universitario Virgen Macarena, Seville

45106

University of Cincinnati Medical Center, Cincinnati

48149

Universitaetsklinik Muenster, Klinik fur Hals-, Nasen- und Ohrenheilkunde, Münster

53228

Allergy, Asthma and Sinus Center, S.C., Greenfield

60637

The University of Chicago, Chicago

65212

University of Missouri, Columbus

72076

Universitätsklinik Tuebingen, Tübingen

75070

Ears Nose and Throat Associates of Texas, McKinney

75209

Alina Clinical Trials, LLC., Dallas

77900

NZZ MUDr Pavel Navratil, Olomouc

78258

Alamo Ent Associates, San Antonio

78759

Orion Clinical Research, Austin

80033

Western States Clinical Research, Inc., Wheat Ridge

83706

Treasure Valley Medical Research, Boise

90006

Sensa Health LA (Sensa Health Clinical Research), Los Angeles

92108

Senta Clinic, San Diego

92782

NewportNativeMD, Inc., Newport Beach

95661

DaVinci, Research LLC, Roseville

98225

Bellingham Asthma, Allergy & Immunology Clinic, Bellingham

33613-3923

University of South Florida, Tampa

02115

Brigham and Women's Hospital, Boston

73120-9389

Allergy, Asthma & Clinical Research Center, Oklahoma City

23507-1904

Eastern Virginia Medical School, Norfolk

40-611

Centrum Medyczne Angelius Provita, Katowice

30-033

"Centrum Medyczne All-Med Badania Kliniczne spolka komandytowa", Krakow

31-513

Centrum Medyczne PROMED, Krakow

05-830

CENTRUM SŁUCHU I MOWY Sp. z o.o., Nadarzyn

47-100

Centrum Medyczne Lucyna Andrzej Dymek s.c, Strzelce Opolskie

08022

Centro Médico Teknon, Barcelona

All Listed Sponsors
lead

Upstream Bio Inc.

INDUSTRY

NCT06164704 - A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps | Biotech Hunter | Biotech Hunter