Effect of Suicidality on Social Cognition

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
SuicideMajor Depressive Disorder
Interventions
BEHAVIORAL

Clinical Interview

A study team member will meet the participant to ask questions regarding the degree of depression at the beginning of the study. This interview will take approximately 1 hour.

BEHAVIORAL

Clinical Questionnaires

A study team member will ask the participant to complete questionnaires assessing the severity of the participant's depression, daily activities, personality/traits, and quality of life. If the participant opts to complete these questionnaires at home, they will be emailed them within 24 hours of this visit. These questionnaires will take approximately 1-2 hours.

OTHER

Brain Scan

The participant will be asked to undergo a magnetic resonance imaging (MRI) scan to look at the structure and function of their brain. The functional MRI measures the level of blood flow to areas of the brain associated with mood and behaviour, and the participant will be asked to complete two behavioural games while they are in the scanner. During the scan, the participant will be required to lie on a table within the cylindrical tube of the MRI scanner in order to complete the scan. This will result in limited movement for the duration of the scan. The scan will take approximately 60 minutes.

BEHAVIORAL

Behavioural Games

The participant will be asked to complete two behavioural games inside the scanner. One of these games includes a monetary payout. They will be given instructions about these tasks outside of the scanner.

Trial Locations (1)

M5B1M8

RECRUITING

Unity Health Toronto, Toronto

All Listed Sponsors
lead

Unity Health Toronto

OTHER