NCT06159608View on ClinicalTrials.gov

Sex Differences in the Vascular Effects of E-cigarette Use

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

December 2, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
E-cigarette Use
Interventions
DRUG

Local heating + L-NAME (NG-nitro-L-arginine methyl ester; nitric oxide synthase inhibitor)

Differences in endothelium- and nitric oxide (NO)-dependent dilation between groups

OTHER

Chronic estrogen exposure

differences in urine estrogen levels across the menstrual cycle between women groups only

Trial Locations (1)

52242

RECRUITING

University of Iowa, Iowa City

All Listed Sponsors
lead

Anna Stanhewicz, PhD

OTHER