NCT06158230View on ClinicalTrials.gov

Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis.

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

March 19, 2023

Primary Completion Date

November 25, 2023

Study Completion Date

January 15, 2024

Conditions
Migraine
Interventions
DRUG

Pizotifen

Pizotifen will be given only at night time to avoid daytime somnolence. Starting dose will be 0.5mg then gradually increased to 1.5 mg

DRUG

Amitriptyline-propranolol

"Amitriptyline will be given at bedtime only, starting at 10 mg daily and gradually increasing to 25 mg daily.~Propranolol will be started in 40 mg daily in divided doses, which gradually increases to 80 mg daily in divided doses"

Trial Locations (1)

1200

Bangabandhu Sheikh Mujib Medical University, Dhaka

All Listed Sponsors
lead

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

OTHER