Cadonilimab + FOLFOX Versus FOLFOX in the Neoadjuvant Treatment of pMMR/MSS Locally Advanced Colorectal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

November 1, 2026

Study Completion Date

November 1, 2028

Conditions
Locally Advanced Colorectal Carcinoma
Interventions
DRUG

Cadonilimab

PD-1/CTLA-4 bi-specific antibody

DRUG

FOLFOX regimen

FOLFOX chemotherapy

Trial Locations (1)

100038

RECRUITING

Cancer Hospital/ National Cancer Center, Chinese Academy of Medical Sciences, Beijing

All Listed Sponsors
lead

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER