Study on the Improvement of Myocardial Microcirculation After Acute Anterior Myocardial Infarction

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

December 20, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

June 30, 2025

Conditions
Intravascular Imaging and Microvascular Obstruction
Interventions
PROCEDURE

OCT-guided PCI

The OCT guidance team routinely conducts OCT examinations on patients after standard angiography and/or thrombus aspiration. The OCT examination follows a standard procedure. The operator evaluates the stability of the lesion and decides whether to proceed with stent implantation therapy (with the option to choose the type of stent) or opt for conservative medical treatment. If a stent is implanted, the procedure is carried out according to guidelines and standard protocols, with the landing zone of the stent determined based on OCT image features. After stent implantation, a follow-up OCT examination of the stent segment, as well as angiographic examination, is performed. Based on the OCT results, the operator decides whether post-dilation is necessary.

PROCEDURE

60 MHz HD-IVUS-guided PCI

The IVUS guidance team routinely conducts IVUS examinations on patients after standard angiography and/or thrombus aspiration. The IVUS examination follows a standard procedure. The operator evaluates the stability of the lesion and decides whether to proceed with stent implantation therapy (with the option to choose the type of stent) or opt for conservative medical treatment. If a stent is implanted, the procedure is carried out according to guidelines and standard protocols, with the landing zone of the stent determined based on IVUS image features. After stent implantation, a follow-up IVUS examination of the stent segment, as well as angiographic examination, is performed. Based on the IVUS results, the operator decides whether post-dilation is necessary.

PROCEDURE

Angiography-guided PCI

After routine angiography and/or thrombus aspiration, the operator assesses the lesion based on treatment standards to determine whether stent implantation is necessary. For patients undergoing stent implantation, a follow-up angiography is performed postoperatively, and the decision for post-dilation is made by the operator based on experience.

Trial Locations (1)

Unknown

RECRUITING

The 2nd Affiliated Hospital of Harbin Medical University, Harbin

All Listed Sponsors
lead

Harbin Medical University

OTHER