Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

October 1, 2023

Study Completion Date

October 1, 2023

Conditions
Periodontitis
Interventions
DRUG

Subgingival application of L-PRF loaded with metronidazole

After phase I therapy, L-PRF loaded medical grade metronidazole was applied sub gingivally into the pockets using blunt gauge needle and Perio-pack was placed (two applications with one week apart were applied subgingivally.

OTHER

Subgingival application of L-PRF

The L-PRF alone was applied subgingivally into the pockets and Perio-pack was placed (two applications with one week apart.

Trial Locations (1)

Unknown

Faculty of Dentistry, Alexandria University, Alexandria

All Listed Sponsors
lead

Yasmeen Khaled

OTHER