Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)

NARecruitingINTERVENTIONAL
Enrollment

1,384

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

December 1, 2026

Study Completion Date

December 1, 2029

Conditions
Rectal Cancer
Interventions
PROCEDURE

Dissection of the No.253 lymph node

The range of the No.253 lymph node is as follows: medially, it extends from the root of the inferior mesenteric artery to the starting section of the left colonic artery; caudally, from the starting point of the left colonic artery to the intersection with the inferior mesenteric vein; laterally, it is bordered by the outer margin of the inferior mesenteric vein; and cranially, from the horizontal section of the duodenum to the beginning of the jejunum. In the controlled group, the surgery is performed with dissection of the No.253 lymph node.

PROCEDURE

Omitting the dissection of the No.253 lymph node

In the experimental group, the surgery is performed without dissection of the No.253 lymph node.

Trial Locations (8)

100021

RECRUITING

Peking Union Medical College Hospital, Beijing

RECRUITING

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

100029

NOT_YET_RECRUITING

China-Japan Friendship Hospital, Beijing

100141

NOT_YET_RECRUITING

Chinese PLA General Hospital, Beijing

100142

NOT_YET_RECRUITING

Beijing Cancer Hospital, Beijing

200025

NOT_YET_RECRUITING

Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai

200032

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

610044

NOT_YET_RECRUITING

West China Hospital Sichuan University, Chengdu

All Listed Sponsors
collaborator

Peking Union Medical College Hospital

OTHER

collaborator

China-Japan Friendship Hospital

OTHER

collaborator

Chinese PLA General Hospital

OTHER

collaborator

Ruijin Hospital

OTHER

collaborator

Fudan University

OTHER

collaborator

West China Hospital

OTHER

collaborator

Peking University Cancer Hospital & Institute

OTHER

lead

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER