A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

285

Participants

Timeline

Start Date

November 16, 2023

Primary Completion Date

March 16, 2030

Study Completion Date

March 16, 2030

Conditions
LymphedemaLymphedema ArmLymphedema of Upper ArmBreast CancerBreast CarcinomaFemale Breast Cancer
Interventions
PROCEDURE

Immediate Lymphatic Reconstruction

Immediate Lymphatic Reconstruction will happen at the time of Axillary Lymph Node Dissection

DIAGNOSTIC_TEST

Volumetric arm measurements

Volumetric arm measurements will occur at each in-person postoperative visit time points.

OTHER

Lymphatic massage

Participants will begin self-directed lymphatic massage 24 to 48 h after surgery and will continue to do lymphatic massage 3 times a week for 3 months after surgery or until 3 months after any adjuvant treatments (chemotherapy, radiation, etc.) are completed

OTHER

Range of motion exercises

Participants will begin self-directed lymphatic massage 24 to 48 h after surgery and will continue to do lymphatic massage 3 times a week for 3 months after surgery or until 3 months after any adjuvant treatments (chemotherapy, radiation, etc.) are completed

OTHER

Compression garment use

Participants will use compression garments 24 to 48 h after surgery and will continue daily use for at least 8 h a day for 3 months or until 3 months after any adjuvant treatments are completed

Trial Locations (7)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York

10604

RECRUITING

Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison

11553

RECRUITING

Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale

11725

RECRUITING

Memorial Sloan Kettering Commack (Limited Protocol Activities), Commack

07920

RECRUITING

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge

07748

RECRUITING

Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown

07645

RECRUITING

Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER