Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models

Active, not recruitingOBSERVATIONAL
Enrollment

6,000,000

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2027

Conditions
Predictive Cancer Model
Interventions
OTHER

Liver Risk Computation Model (LIRIC)

A neural network model (LIRIC-NN) and a logistic regression model (LIRIC-LR) that use routinely collected EHR data to stratify individuals into HCC risk groups for the general population

OTHER

Liver Risk Computation Model (LIRIC)_cirrhosis

A neural network model (LIRIC-NN) and a logistic regression model (LIRIC-LR) that use routinely collected EHR data to stratify individuals into HCC risk groups for the population with liver cirrhosis

OTHER

Liver Risk Computation Model (LIRIC)_no_cirrhosis

neural network model (LIRIC-NN) and a logistic regression model (LIRIC-LR) that use routinely collected EHR data to stratify individuals into HCC risk groups for the population without liver cirrhosis

Trial Locations (1)

02115

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Massachusetts Institute of Technology

OTHER

collaborator

TriNetX, LLC

UNKNOWN

lead

Beth Israel Deaconess Medical Center

OTHER