NCT06138821View on ClinicalTrials.gov

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 24, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
ObesityLiver DiseasesLiver FibrosisLiver FatMetabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated SteatohepatitisMASLDMASHWeight LossInsulin ResistanceInsulin SensitivityInsulin Sensitivity/ResistanceMetabolic DiseaseDiabetesDiabetes Mellitus, Type 2NASH With FibrosisNon-Alcoholic Fatty Liver DiseaseNon Alcoholic Fatty LiverNon-alcoholic Steatohepatitis
Interventions
DEVICE

ESG + lifestyle modification

Endoscopic sleeve gastroplasty - an endoscopic weight loss procedure where an endoscopic suturing device is utilized to reduce the size of the stomach by 70%.

BEHAVIORAL

Lifestyle modification

Lifestyle modification program consisting of diet and exercise therapy

Trial Locations (1)

02115

RECRUITING

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Pichamol Jirapinyo, MD, MPH

OTHER