Intraoperative Autonomic Neural Blockade

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

December 2, 2023

Primary Completion Date

April 2, 2024

Study Completion Date

May 2, 2024

Conditions
Pain, PostoperativeNausea, PostoperativeVomiting, PostoperativeAnalgesiaOpioid Use
Interventions
DRUG

Local anesthetic injection Bupivacaine plus dexamethasone

The autonomic neural block is performed with a 25-gauge needle attached to a venous catheter extension introduced through the left 12-mm port. Infiltration of 20 mL of non-diluted 0.5% bupivacaine plus dexamethasone 8 mg is performed at the celiac plexus and vagus nerve trajectory.

DRUG

Local anesthetic injection bupivacainde plus dexamethasone plus a colloid

bupivacaine plus dexamethasone 8 mg plus a colloid 10 cc (Gelofucin, B. Braun Medical S.A., Crissier, Suiza.) is performed at the celiac plexus and vagus nerve trajectory.

DRUG

Local anesthetic injection bupivacaine plus clonidine

bupivacaine 5% plus clonidine (0,150mgs) is performed at the celiac plexus and vagus nerve trajectory

All Listed Sponsors
lead

Universidad Simón Bolívar

OTHER