Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

November 30, 2023

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2025

Conditions
Asthma in ChildrenAsthma Attack
Interventions
DRUG

Magnesium Sulfate within the first hour

"The experimental group will receive 40-50 mg/kg of IV magnesium sulfate will be given to the experimental group alongside the first line asthma therapies (ie inhaled beta agonists, IV steroids). This will be given with a 20 mL/kg normal saline bolus (max 1000 mL) to avoid possible hypotension.~15-19 kg: 750 mg~20-29 kg: 1000 mg~30-39 kg: 1500 mg~\>40 kg: 2000 mg"

OTHER

No Magnesium sulfate within the first hour

The control group will not receive IV magnesium sulfate within the first hour of treatment.

Trial Locations (1)

73104

RECRUITING

Oklahoma Children's Hospital, Oklahoma City

All Listed Sponsors
lead

University of Oklahoma

OTHER