Computed Guided Prolotherapy Versus Conventional Prolotherapy

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 2, 2021

Primary Completion Date

October 14, 2022

Study Completion Date

October 14, 2022

Conditions
Temporomandibular Joint DisordersOrofacial Pain
Interventions
PROCEDURE

Conventional arthrocentesis followed by I-PRF injection

An auriculotemporal nerve block using Mebacaine 0.5% was administered near the mandible's neck. The patient sat at a 45° angle with their head turned. The posterior entry point was 10 mm from the midtragus and 2 mm below the line, while the anterior entry point was marked 20 mm from the midtragus and 10 mm below the line. A biting block kept the mouth open. 2-3 ml of Ringer lactate was injected with an 18-gauge needle to enlarge the joint space. A second needle allowed the solution to flow freely. After lavaging the joint, 1 ml of I-PRF was injected into the upper joint space. Jaw manipulation was done to address adhesions and improve disc mobility.

PROCEDURE

3d surgical guided Arthrocentesis followed by I-PRF injection

Patients underwent arthrocentesis with Ringer lactate, followed by I-PRF injection in the TMJ's superior space using a CT-planned 3D-printed guide. Positioned at a 45° angle, patients were comfortably seated, and disinfection was performed. The patient-specific guide, fitting over maxillary teeth and the face, was employed unilaterally or bilaterally with a biting block for mouth opening maintenance. An 18-gauge needle administered 2-3 ml of Ringer lactate, widening the joint space, followed by a second needle allowing free solution flow (80-90 ml) to flush the superior joint space. Post-arthrocentesis, 1 ml of I-PRF was injected. To enhance joint mobility and free the disc, gentle manipulation of the lower jaw was performed after removing the needles and guide.

Trial Locations (1)

Unknown

Faculty of Dental Medicine - Al-Azhar University, Asyut

All Listed Sponsors
lead

Al-Azhar University

OTHER

NCT06132594 - Computed Guided Prolotherapy Versus Conventional Prolotherapy | Biotech Hunter | Biotech Hunter