Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice

PHASE3RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

April 25, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

May 26, 2026

Conditions
PeriodontitisPeriodontal DiseasesPeriodontal Pocket
Interventions
DRUG

Amoxicillin

Amoxicillin belongs to the penicillin category, and it is a commonly prescribed broad-spectrum antibiotic as a periodontal treatment adjunct.

DRUG

Metronidazole

Metronidazole is effective against anaerobic bacteria, and it is often combined with Amoxicillin for an enhanced antimicrobial effect as a periodontal treatment adjunct.

OTHER

Placebo

Placebo in identical drug-safe vials with capsules identical in appearance to the active drugs

Trial Locations (1)

35233

RECRUITING

University of Alabame, Birmingham

All Listed Sponsors
collaborator

National Institute of Dental and Craniofacial Research (NIDCR)

NIH

collaborator

National Dental PBRN

UNKNOWN

lead

Rutgers, The State University of New Jersey

OTHER