NCT06126991View on ClinicalTrials.gov

Organ Protective Effect of Cetirizine In Patients With Severe Burns

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

January 23, 2024

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2025

Conditions
Burns
Interventions
DRUG

Cetirizine

Oral administration of cetirizine at 10mg once daily will be used.

DRUG

Midazolam and Fentanyl

Midazolam 50mg + fentanyl 300ug micro pump push will be used with a starting dose of 5ml/hour, adjusted according to the patient's level of sedation. The patient's RASS score will be maintained between -1-0 and the drug will be suspended with a blood pressure below 90/60mmHg.

Trial Locations (1)

Unknown

RECRUITING

Department of Burn, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
lead

Ruijin Hospital

OTHER