Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

single dose of ketamine (0.71mg/kg bodyweight i.v. over 40 minutes)

single dose of placebo (0.9% saline solution i.v. over 40 minutes)

Real-time fMRI based neurofeedback over 20 minutes where participants are instructed to perform reward imagery. The feedback is based on an experimental region. The training is repeated three times.

Sham real-time fMRI neurofeedback training over 20 minutes where participants are instructed to perform reward imagery. The feedback is based on a control region. The training is repeated three times.