Comparison Of Percutaneous Mechanical Thrombectomy With Different Access in Treatment of Acute Deep Venous Thrombosis

RecruitingOBSERVATIONAL
Enrollment

210

Participants

Timeline

Start Date

January 1, 2021

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2027

Conditions
Deep Vein Thrombosis
Interventions
PROCEDURE

Percutaneous mechanical thrombectomy (PMT) by the modified approach

The modified approach includes the ipsilateral calf venous access and the contralateral femoral venous access. Through contralateral femoral venous access, a hydrophilic guide wire and a catheter will be crossover through the thrombus side to the distal calf vein. The ipsilateral calf venous access will be punctured under the guidance of ascending venography. A hydrophilic guide wire and a catheter will be used to pass through the thrombus antegrade to the inferior vena cava. Percutaneous mechanical thrombectomy (PMT) catheter will be used to clear the thrombus. After PMT treatment, residual thrombus will be reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) will be conducted if there is residual thrombus. Percutaneous balloon angioplasty (PTA) and stenting will be conducted if there is \>50% stenosis of the diameter of the iliac vein.

PROCEDURE

Percutaneous mechanical thrombectomy (PMT) by the traditional approach

The traditional approach will be punctured from the ipsilateral popliteal vein under ultrasound guidance. A hydrophilic guide wire and a catheter will be used to pass through the thrombus antegrade to the inferior vena cava. Percutaneous mechanical thrombectomy (PMT) catheter will be used to clear the thrombus. After PMT treatment, residual thrombus will be reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) will be conducted if there is residual thrombus. Percutaneous balloon angioplasty (PTA) and stenting will be conducted if there is \>50% stenosis of the diameter of the iliac vein.

Trial Locations (1)

200127

RECRUITING

Renji Hospital, Shanghai

All Listed Sponsors
collaborator

First People's Hospital of Hangzhou

OTHER

collaborator

Chengdu University of Traditional Chinese Medicine

OTHER

lead

RenJi Hospital

OTHER