An Investigator-initiated Linked Study to OCEANIC-AF

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

November 3, 2023

Primary Completion Date

September 17, 2026

Study Completion Date

September 17, 2026

Conditions
Atrial Fibrillation
Interventions
DIAGNOSTIC_TEST

Thrombotic assessment

"GTT~The Global Thrombosis Test (GTT) (Thromboquest Limited, UK) is an in vitro method imitating high shear stress conditions akin to that which exist in a severely stenosed artery. The test measures platelet reactivity (occlusion time) and endogenous fibrinolysis time (lysis time).~TEG Thromboelastography (TEG, Haemonetics Corporation, USA) is a technique that assesses the whole process of clotting and its viscoelastic properties, from the initial activation and aggregation of platelets, to the role of thrombin and finally the stability of the formed clot, as a measure of fibrinolytic resistance.~Citrated plasma will be stored for subsequent evaluation of thrombosis and fibrinolysis markers (including but not restricted to D-dimer, PAI-1, hs-CRP, NETs)"

Trial Locations (2)

Unknown

NOT_YET_RECRUITING

Liverpool Heart and Chest Hospital, Liverpool

RECRUITING

East and North Herts NHS Trust, Stevenage

All Listed Sponsors
collaborator

Liverpool Heart and Chest Hospital NHS Foundation Trust

OTHER

lead

East and North Hertfordshire NHS Trust

OTHER_GOV