300
Participants
Start Date
April 16, 2024
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2026
Vitamin C
Drug: Patients in the intervention group will receive 2g Vitamin C orally within 4 hours of the start of the surgery followed by 500 mg of Vitamin C to be taken orally twice a day from post-op day1 to day 56.
Placebo
Drug: Patients in the placebo group will receive identical placebo capsules taken orally within 4 hours of the start of the surgery followed by placebo capsules taken orally twice a day from post-op day 1 to day 56.
RECRUITING
Sunnybrook - Holland Centre, Toronto
RECRUITING
Mount Sinai Hospital, Toronto
RECRUITING
Toronto Western Hospital, Toronto
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
The Arthritis Society, Canada
OTHER
University Health Network, Toronto
OTHER