Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients

PHASE3Enrolling by invitationINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 13, 2023

Primary Completion Date

September 23, 2025

Study Completion Date

December 31, 2025

Conditions
Decompensated Cirrhosis and Ascites
Interventions
DRUG

Branched-chain amino acid

Oral branched-chain amino acid is provided to the patients with a recommended daily intake of approximately 13.68 grams per day. Each sachet contains 6.84 grams of BCAA (valine 1.82 grams, leucine 3.29 grams, isoleucine 1.72 grams), total protein 17.08 grams, carbohydrates 25.48 grams, fat 5.66 grams, providing 221.2 kcal of energy. Each sachet weighs 52 grams and should be mixed with 150 ml of water. The recommended daily intake is 2 sachets, to be consumed after breakfast and dinner. The BCAA provided to the patients comes in pre-packaged silver sachets, with the manufacturing date and expiration date indicated.

Trial Locations (1)

10700

Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, Bangkok

All Listed Sponsors
lead

Mahidol University

OTHER