Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

May 2, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2029

Conditions
Hemophilia B
Interventions
GENETIC

ANB-002, dose 1

Adeno-associated viral vector carrying the FIX gene single infusion at dose 1.

GENETIC

ANB-002, dose 2

Adeno-associated viral vector carrying the FIX gene single infusion at dose 2.

GENETIC

ANB-002, dose 3

Adeno-associated viral vector carrying the FIX gene single infusion at dose 3.

Trial Locations (17)

125167

RECRUITING

"Federal State Budgetary Institution National Medical Research Centre for Hematology of the Ministry of Health of Russian Federation (Department of Clinical Diagnostics for Hematology and Hemostasis Disorders)", Moscow

RECRUITING

"Federal State Budgetary Institution National Medical Research Centre for Hematology of the Ministry of Health of Russian Federation (Department of Traumatology and Reconstructive and Restorative Orthopedics for Patients with Hemophilia)", Moscow

125284

RECRUITING

"Federal Budgetary Institution Moscow City Clinical Hospital named after S. P. Botkin", Moscow

167904

RECRUITING

"State Institution Komi Republican Oncological Dispensary", Syktyvkar

188300

RECRUITING

State budgetary healthcare institution Leningrad Regional Clinical Hospital, Gatchina

191024

RECRUITING

Russian Research Institute of Hematology and Transfusiology Federal State Institution of Federal Medical and Biological Agency, Saint Petersburg

191186

RECRUITING

City Polyclinic №37, Saint Petersburg

197341

RECRUITING

Almazov National Medical Research Centre, Saint Petersburg

220089

RECRUITING

Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology, Minsk

246040

RECRUITING

Republican Scientific and Practical Center for Radiation Medicine and Human Ecology, Homyel

443099

RECRUITING

"Federal State Budgetary Educational Institution of Higher Education Samara State Medical University of the Ministry of Healthcare of the Russian Federation", Samara

450008

RECRUITING

"Federal State Budgetary Educational Institution of Higher Education Bashkir State Medical University of the Ministry of Healthcare of the Russian Federation", Ufa

454048

RECRUITING

"State Autonomous Institution for Healthcare Chelyabinsk Regional Clinical Hospital", Chelyabinsk

603137

RECRUITING

"LLC Medis", Nizhny Novgorod

610027

RECRUITING

"Federal State Budgetary Organization of Science Kirov Research Institute of Hematology and Blood Transfusions of Federal Medical Biological agency", Kirov

630087

RECRUITING

State Novosibirsk Regional Clinical Hospital, Novosibirsk

650066

RECRUITING

Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biocad

INDUSTRY